Exploration of Novel Therapeutic Strategies for the Treatment of Diabetes Mellitus

Publicado 2023-04-23
Seção Research Articles

Autores

  • Shaista Mumtaz Department of Eastern Medicine, University of Poonch Rawalakot Azad Jammu and Kashmir-Pakistan
  • Abid Rashid Faculty of Medical Sciences, Government College University Faisalabad, Pakistan
  • Muhammad Akram Department of MBA, Jyoti Nivas College Autonomous, Bangalore, India
  • Umme Laila Department of Eastern Medicine, Government College University Faisalabad, Pakistan
  • Momina Iftikhar Department of Eastern Medicine, Government College University Faisalabad, Pakistan
  • Hina Anwar Department of Eastern Medicine, Government College University Faisalabad, Pakistan
  • Rida Zainab Department of Eastern Medicine, Government College University Faisalabad, Pakistan
  • Muhammad Talha Khalil Department of Eastern Medicine, Government College University Faisalabad, Pakistan
  • Abolfazl Jafari-Sales Department of Microbiology School of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran
  • Walaa Fikry Elbossaty 5 Department of Biochemistry, Damietta University, Egypt
  • El Hadji Seydou Mbaye BCNet International Working Group, IARC/WHO, Dakar –Senegal
  • Muhammad Mahran Aslam Nuclear Institute of Agriculture (NIA), Tando Jam, 70060, Sindh, Pakistan
  • Mohamed M. Amer Prof. of Poultry Diseases, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
  • Ravindra Prasad Aharwal Institute Name: Department of Botany, Rajabhoj Government College, Katangi, Balaghat - 481445 (M.P.), India
  • Gaweł Sołowski Gdansk University of Technology Faculty of Mecanical Engineering, Poland
  • Mourad Ben Said Service de Microbiologie et Immunologie, Ecole Nationale de Médecine Vétérinaire, Univ. Manouba, 2020 Sidi Thabet, Tunisia.

DOI:

https://doi.org/10.7770/safer-V13N2-art3005

Resumo

Diabetes mellitus (DM) is a disorder in which the body does not produce enough or respond to insulin normally, resulting in an abnormal increase in blood glucose levels. 90% of diabetes cases in pregnant women are gestational diabetes mellitus (GDM). It is known that fluctuations in the level of glucose and its irregularity led to disturbances in the health of both mother and fetus.The therapeutic strategies and options for the treatment of gestational diabetes are highlighted in this review. We havereviewed medicinal plants used in the treatment of gestational diabetes. Literature review indicates that medicinal plants are effective in treating osteoarthritis and have been clinically and scientifically proven. Natural medicines have been the subject of chemical studies and many plants are the subject of clinical trials. Their results are remarkable and significant. However, scientific exploration for bioactive constituents is becoming increasingly important and their mechanisms of actions to treat GDM are still ongoing.