Homoeopathic treatment on diabetic distal symmetric polyneuropathy [ddsp]: a systematic review.

Resumo

Background: An epidemic of the disorders/ complications is paralleling the global epidemics of prediabetes and diabetes. The most frequent complication is neuropathy, of which distal symmetric polyneuropathy (DDSP) is very common. Diabetic neuropathy is characterised by pain and significant morbidity, as well as a loss of sensory function that begins distantly in the lower extremities. At least 50% of people with diabetes eventually develop diabetic neuropathy. In patients with type 1 diabetes mellitus, glucose control effectively slows the progression of diabetic neuropathy; however, the effects are less pronounced in patients with type 2 diabetes mellitus. Material and Methods: To locate clinical research publications, a  computerised literature search was conducted. A thorough search of PubMed, Medline, Google Scholar, ScienceDirect, and the Thieme-E-journal of homoeopathy was done. This review only included clinical studies that involved humans. Pilot research, animal experiments  were excluded. All prospective observational clinical research studies that were randomised, double-blind, and placebo-controlled were included. Conclusion: This systematic review concluded that homeopathic medicines are safe and effective in management of Diabetic Distal Symmetric Polyneuropathy (DDSP). But more randomized placebo controlled studies should be conducted to strengthen the available evidence.